6. How Is The Calculation Derived For A Drug To Be Bio Equivalent With Other? On Which Base The Limit Is Fixed As 80-120% For A Drug To Be Bio Equivalent. What Is Meant By 90% Confidential Interval?
To be "bioequivalent" two preparations or drugs need to give the same biological effect. The usual "experimental error" put on this is 20% - thus, 80-120% is considered "bioequivalent.” 90 percentage confidence interval means that statistically it is 90% certain that the results are equivalent.
