Which of these is not an important component of initiation of parturition in humans ? (1) Increase in estrogen and progesterone ratio (2) Synthesis of prostaglandins (3) Release of Oxytocin (4) Release of Prolactin
Option 4) Release of Prolactin is not an important component of initiation of parturition in humans. Towards the end of pregnancy, the increasing ratio of estrogen to progesterone promotes uterine contractions. Progesterone no longer inhibits them. High levels of estrogens increase the number oxytocin receptors and gap junctions in the myometrium. Prostaglandins induce the softening of uterine cervix and enhance uterine contractile strength.
