Name negatively and positively charged components of nucleosome.

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Muskan Anand

2 years ago

 A nucleosome is composed of histone protein and DNA. DNA carries the negative charge due to the phosphodiester linkage and histone is basic in nature and carries a positive charge because histones are made up of basic amino acids. DNA wrapped around the histone octamer (H2A-H2B, H3, H4 two copies of each) through the H- bonding. So, the negatively charged component of the nucleosome is DNA and the positively charged components of nucleosomes are histone octamer.

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