What happens in sickle-cell anaemia : A. Loss of chromosomes B. Gain of whole set of chromosomes C. Deletion of Valine at 6th position of beta globin chain D. Substitution of glutamic acid by Valine
Option D Sickle cells that block blood flow to organs deprive the affected organs of blood and oxygen. In sickle cell anemia, blood is also chronically low in oxygen. This lack of oxygen-rich blood can damage nerves and organs, including kidneys, liver and spleen, and can be fatal.
