Cyclosporin A is used as an immunosuppressive agent. II. It is because, this molecule has the ability to inhibit the enzyme responsible for synthesis of cholesterol A. Both statements correct, 2nd is correct explanation of 1st B. Statement 1 is incorrect, 2 is correct C. Both 1&2 correct, but 2nd st. Is not right explanation of 1 D. Statement 1 is correct, 2nd is incorrect
Option D The mechanism of action of cyclosporine is as a calcineurin inhibitor, a cytochrome P450 3A4 inhibitor, and a P-glycoprotein inhibitor. Cyclosporin A (CsA) inhibits the synthesis of interleukins (IL), including IL-2, which is essential for the self-activation of T lymphocytes (LT) and their differentiation.
