A single stranded DNA or RNA, tagged with a radioactive molecule is allowed to hybridize to it complementary DNA in a clone of cells followed by detection using a. Polymerase chain reaction b. Biolistic or gene gun c. Autoradiography d. DNA fingerprinting
Option C. A single stranded DNA or RNA joined with a radioactive molecule (probe) is allowed to hybridise to its complementary DNA in a clone of cells. It is followed by detection using autoradiography. The clone having the mutated gene will not appear on the photographic film, because the probe will not have the complementarity with the mutated gene.