When aspirin (an acid) is in the stomach (an acidic environment), what may be said of the aspirin molecules? A. Most molecules will be un-ionised and therefore able to be pass through the stomach mucosa. B. Most molecules will be ionised and therefore able to be pass through the stomach mucosa. C. Most molecules will be un-ionised and therefore NOT able to be pass through the stomach mucosa. D. Aspirin will be in the form of its salt and therefore able to be pass through the stomach mucosa.
Option A.Aspirin in an acidic surroundings might be in its molecular form (and un-ionised). This makes it soluble in non-polar media just like the plasma membrane (that's lipid). Being soluble in lipid, molecular aspirin is in a position to be absorbed from the stomach