Explain the autoregulatory mechanism of GFR.
This mechanism in Kidney is present to regulate the glomerular filtrate rate. Juxtaglomerular apparatus (JGA) is a specialized cellular region located where the distal convoluted tubule and afferent arteriole, come in contact with each other. A fall in GFR can activate the JG cells to release renin which acts through a complex series of reactions called renin-angiotensin aldosterone mechanism, which can stimulate blood flow and thereby the GFR back to normal.
