What do you understand about “Donnan Equilibrium''?
Donnan Equilibrium theory suggests that the passive accumulation of ions which are fixed on is non-diffusible, against an ECP gradient. It is a membrane that separates a cell from the external medium and allows the exchange of some ions and not the other. On the inner side of this membrane are anions (fixed and non-diffusible). The membrane becomes impermeable to these anions. In such conditions (for equilibrium) mobile cations are needed to balance the negative charges of the anions. According to it, Donnan equilibrium is reached, if the product of anions and cations in the internal solution becomes equal to the product of anions and cations in the external solution. [Ci + ] [Ai - ] = [Co + ] [Ao - ][Ci + ] [Ai - ] = [Co + ] [Ao - ] Where Ci + Ci + = cations inside Ai - Ai - = Anions in side Co + Co + = Cations outside Ao - Ao - = Anions outside.
