Mention any two autosomal genetic disorders with their symptoms.
Two autosomal genetic problems are as follows. 1. Sickle mobileular Anaemia It is an autosomal related recessive disease, that is resulting from factor mutation withinside the beta-globin chain of haemoglobin pigment of the blood. The ailment is characterised through sickle formed crimson blood cells, that are formed because of the mutant haemoglobin molecule. The disorder is managed via way of means of Hb A and Hb S allele. The homozygous people with genotype, Hb SHb S , display the signs and symptoms of this disorder whilst the heterozygous people with genotype, Hb A Hb S , aren't affected. However, they act as vendors of the ailment. Symptoms Rapid coronary heart rate, breathlessness, not on time boom and puberty, jaundice, weakness, fever, immoderate thirst, chest pain, and reduced fertility are the main signs of sickle mobileular anaemia ailment. (b) Down's syndrome It is an autosomal sickness this is as a result of the trisomy of chromosome 21. Symptoms The person is brief statured with spherical head, open mouth, sticking out tongue, brief neck, slanting eyes, and broad brief hands. The man or woman additionally indicates retarded intellectual and bodily boom.
