How is early detection of infectious diseases possible by molecular diagnostics?
Molecular diagnostic of early detection of infectious diseases: A low concentration of viral or bacterial DNA in a host body can be detected (much before the symptoms of the disease appear) by polymerase chain reaction (amplification). Clones of genes can be used as probes to detect the presence of complementary (normal) strands of DNA in a mutant-clone. Hybridization does not occur and hence the radioactivity does not appear in the (autoradiography) photographic films.
