Discuss the significance of the heavy isotope of nitrogen in Meselson and Stahl’s experiment.
By using the heavy isotope of nitrogen, they could find out the semiconservative nature of DNA replication as the densities of DNA having 15N in both the strands 15N/14N DNA and 14N/14N DNA were all different. The hybrid DNA (15N/14N DNA) had a density intermediate between that of heavy DNA (15N/15N DNA) and that of light/normal DNA (14N/14N DNA).
