Explain the role of tRNA in the initiation of protein synthesis
Role of tRNA’ in the initiation of protein synthesis: tRNA is an adapter molecule that on one hand would bind to a specific amino acid. The tRNA then called sRNA (soluble RNA). tRNA has an anticodon loop that has bases complementary to the code. It has an amino acid acceptor end to which it binds to an amino acid. tRNAs are specific for each amino acid. For initiation, there is another tRNA, that is referred to as initiator tRNA. Amino acids are activated in the presence of ATP and joined to their corresponding tRNA it is called charging of tRNA or aminoacylation of tRNA. Two such charged tRNAs are brought close and the formation of peptide bond occurs
