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Preeti Tripathi

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English
1 year ago

4. Why Is Buprenorphine Less Addictive Than Other Opioids (like Fentanyl) - Is It Explainable By Its Strength Of Binding To The Common Receptor, Or?

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Abhishek Mishra

1 year ago

Buprenorphine is what is referred to as a partial agonist - i.e. it binds to the receptor but even at its maximum cannot give as much of an effect as a full agonist (such as morphine) - it is, thus, also a partial antagonist (partially inhibits the actions of full agonists).

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