An hypothesis for the extinction of the dinosaurs is that the earth had been hit by a gigantic meteor that caused the death of those big reptiles. In that case the entire genetic pool of those animals has been destroyed, invalidating the Hardy-Weinberg equilibrium. In Genetics what is this type of gene frequency change called?
The phenomenon in which a large number of genes is destroyed or introduced in a population is called genetic drift. When a genetic drift occurs the Hardy Weinberg principle is not applicable.