22.A toxic substance released from ruptured RBCs in case of malaria, responsible for causing chill and high fever is: A. Haemozoin B. Haematozoin C. Haematuria D. Haemoglobin
Option A. In malaria, chills and shivers are caused by the release of the toxic substance haemozoin into the blood at the time of RBC's rupture. It is generally followed by fever.
