A wound stimulates the platelets in the blood to release blood coagulating factors to initiate the mechanism of coagulation.
1. Platelets release the plasma protein thromboplastin.
2. Thromboplastin converts prothrombin, which is also a plasma protein into the enzyme thrombin.
3. Thrombin converts fibrinogen into fibrin.
4. Fibrin is insoluble protein and forms the threads that bind the clot.
Blood clotting prevents the excessive loss of blood from the body.