Adenosine deaminase deficiency can be permanently cured by which of the following methods? (A) Bone marrow transplantation (B) Enzyme replacement therapy (C) Gene therapy at early embryonic stages (D) All of these
Option C. Adenosine deaminase (ADA) deficiency can be treated by bone marrow transplantation, or by enzyme replacement therapy, in which functional ADA is given to the patient by injection. But permanent treatment can be done by introduction of gene isolated from bone marrow cells, which produces ADA, into the cells of the patient at early embryonic stage.
