The absence deaminase deficiency results into (A) Addison’s disease (B) Dysfunction of immune system (C) Parkinson’s disease (D) Digestive disorder
Option B.Adenosine deaminase deficiency is an autosomal recessive metabolic disorder that causes immunodeficiency. ADA deficiency may be present in infancy, childhood, adolescence, or adulthood. ADA deficiency is due to a lack of the enzyme adenosine deaminase. This deficiency results in an accumulation of deoxyadenosine in which T cells undergo proliferation and development in the thymus, affected individuals typically have a small, underdeveloped thymus. As a result, the immune system is severely compromised or completely lacking. Hence, ADA deficiency results in the Inability of the immune system to function normally.
