Maturation of proinsulin into insulin takes place after (A) Joining of C peptide (B) Removal of C peptide (C) Removal of disulphide bridge (D) Addition of disulphide bridge
Option B.Maturation of proinsulin into insulin takes place after removal C peptide. Proinsulin is an inactive and single polypeptide chain of the B and A subunits joined by the C-peptide region. On maturation, the C-chain splits off, resulting in formation of insulin molecule.
