Which is true about enzyme (a) Apoenzyme = Holoenzyme + Coenzyme (b) Holoenzyme = Apoenzyme + Coenzyme (c) Coenzyme = Apoenzyme + Holoenzyme (d) Holoenzyme = Coenzyme - Apoenzyme
Correct option is B) Enzymes work efficiently in association with various factors which enhances it's activity. These factors may be; Coenzymes are organic molecules that are mostly derivatives of vitamins soluble in water by phosphorylation. Example of coenzyme include thiamine pyrophosphate (TPP), flavin adenine dinucleotide (FAD), biotin Apoenzyme is an inactive form of enzyme lacking the association of coenzyme and/or cofactors. Activation of the enzyme occurs upon binding of an organic or inorganic cofactor. Holoenzyme is a complete and catalytically active form of enzyme. An apoenzyme together with its cofactor is holoenzyme. Examples of holoenzymes include DNA polymerase and RNA polymerase which contain multiple protein subunits.